Urgent Demand of the Continual Studies of Drug-Nutrition-Interrelation
نویسنده
چکیده
There are many combinations of drug-drug interactions that have been extensively cited in the literature; on the other hand different food-drug interactions exist and can have serious negative effects on health which must not be discarded. During the present review different points were discussed including effect of drug administration on food utilization, nutritional status and appetite such as effect of drug on eating behavior or macronutrient specific dietary selection and nutrients absorption and metabolism. Effect of drug on vitamin needs, nutrient-nutrient incompatibilities, impact of anti-inflammatory drugs on nutritional status and effect of slimming drugs on serum minerals during consumption of different food were reviewed. Also, effect of the food consumed and nutritional status on the efficiency of drugs was dealt with; such as influence of the type of food, malnutrition and obesity on drug absorption, blood levels and efficiency. Nutritional effect on drug-protein binding in plasma, systemic reactions induced by drug-food incompatibilities and effect of different nutrients on drug biotransformation were discussed. Among the important points which were reviewed id to what extent the consumption of food or nutrient may affect the drug dosage. The present review highlighted the various bioactive components of food that possess medicinal effect.
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